TARGETING SRSF2 MUTATIONS IN LEUKEMIA WITH RKI-1447: A STRATEGY TO IMPAIR CELLULAR DIVISION AND NUCLEAR STRUCTURE

Targeting SRSF2 mutations in leukemia with RKI-1447: A strategy to impair cellular division and nuclear structure

Biscuits Summary: Spliceosome machinery mutations are common early mutations in myeloid malignancies; however, effective targeted therapies against them are still lacking.In the current study, we used an in vitro high-throughput drug screen among four different isogenic cell lines and identified RKI-1447, a Rho-associated protein kinase inhibitor,

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Medical Imaging Workshop for Seniors

Abstract Introduction This health education workshop is designed to provide an older adult audience with basic information on imaging modalities commonly ordered in an emergency department setting.In conceiving the workshop and choosing topics, we conducted a needs assessment with volunteer residents of a senior housing facility.The participants ex

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Update on the evaluation of transient vision loss

John H Pula,1 Katherine Kwan,2 Carlen A Yuen,3 Jorge C Kattah4 1Department of Neurology, 2Department of Night Moisturizers ophthalmology, NorthShore University HealthSystem, Evanston IL, USA; 3University of Illinois College of Medicine at Peoria, 4Department of Neurology, University of Illinois College of Medicine at Peoria, Peoria, IL, USA Abstrac

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